Butea Superba Rosb Extract Pharmacological Assessment for Aphrodisiac Effects

Authors

  • Kushwaha A. K. School of pharmacy, SunRise University, Alwar, Rajasthan 301028
  • Babar V. B. School of pharmacy, SunRise University, Alwar, Rajasthan 301028

DOI:

https://doi.org/10.61554/ijnrph.v1i2.2023.52

Abstract

This study conducted a thorough assessment of the aphrodisiac effects of Butea superba Roxb extract, using multiple parameters to evaluate its influence on male reproductive functions. At first, the researchers compared the androgenic activity to testosterone. They found that the ethanolic extracts group showed a significant increase in body weight, testes, epididymis, seminal vesicles weight, and testosterone levels. These findings indicate notable androgenic effects of the extracts, which may be linked to the plant's androgenic properties. An analysis of sexual performance showed a decrease in the time it took for mounting and initiating sexual activity, along with an increase in the frequency of mounting and sexual activity in the group that received ethanolic extracts. The results of the study suggest an improvement in sexual activity among male rats, as evidenced by an increase in the penile erection index. Through behavioral analysis, it was observed that the group treated with the extract displayed increased exploratory behavior and mounting scores. This indicates an overall improvement in response to sexual stimulus. The testis sections were examined histologically and showed a significant improvement in spermatogenesis, similar to the effects of testosterone. The extracts showed an improvement in spermatogenic activity that varied based on the dosage. In addition, the study revealed that the group treated with ethanolic extracts had higher testosterone levels compared to the control and testosterone groups. This suggests a possible boost in testosterone production.

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Keywords:

Aphrodisiac Activity, Testosterone, Spermatogenesis, Butea Superba, Ethanolic Extract.

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Published

2023-12-30

How to Cite

A. K., K., & V. B., B. (2023). Butea Superba Rosb Extract Pharmacological Assessment for Aphrodisiac Effects. International Journal of Newgen Research in Pharmacy & Healthcare, 1(2), 133–142. https://doi.org/10.61554/ijnrph.v1i2.2023.52

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References

Rullyansyah S, Muzakky F, Samlan K, Hanistya R, Maulidiyanti ETS. Phytochemical screening and evaluation of red ginger extracts on aphrodisiac activity. Gac Med Caracas [Internet]. 2022;130(Supl. 1). Available from: http://dx.doi.org/10.47307/gmc.2022.130.s1.2 6 DOI: https://doi.org/10.47307/GMC.2022.130.s1.26

Asfour HZ, Alhakamy NA, Fahmy UA, Ahmed OAA, Rizg WY, Felimban RI, et al. Zein-stabilized nanospheres as nanocarriers for boosting the aphrodisiac activity of icariin: Response surface optimization and in vivo assessment. Pharmaceutics [Internet]. 2022;14(6). Available from: http://dx.doi.org/10.3390/pharmaceutics14061 279 DOI: https://doi.org/10.3390/pharmaceutics14061279

Praptiwi, Wulansari D, Kamitakahara H, Takano T, Munawarah AU, Agusta A. Evaluation of aphrodisiac activity of yellow ginseng (Rennelia elliptica Korth.) root ethanol extract in male DDY mice (Mus musculus). In: AIP Conference Proceedings. AIP Publishing; 2022. DOI: https://doi.org/10.1063/5.0109989

Kusumawati I, Mahatmaputra S, Hadi R, Rohmania R, Rullyansyah S, Yusuf H, et al. Aphrodisiac activity of ethanolic extracts from the fruits of three pepper plants from Piperaceae family. J Farm Dan Ilmu Kefarmasian Indones [Internet]. 2021;8(2):194. Available from: http://dx.doi.org/10.20473/jfiki.v8i22021.194-199 DOI: https://doi.org/10.20473/jfiki.v8i22021.194-199

Gayathri A G, Mruthunjaya K. Aphrodisiac activity of nutraceuticals. Int J Res Pharm Sci [Internet]. 2020;11(3):3878–88. Available from: http://dx.doi.org/10.26452/ijrps.v11i3.2572 DOI: https://doi.org/10.26452/ijrps.v11i3.2572

Singh SK, Jain AP, Tandon M. Investigations on Citrullus colocynthis seeds for aphrodisiac activity in male albino rats. Adv Pharm J [Internet]. 2020;5(3):119–22. Available from: http://dx.doi.org/10.31024/apj.2020.5.3.6 DOI: https://doi.org/10.31024/apj.2020.5.3.6

Aydogan F, Baykan S, Soliman GA, Yusufoglu H, Bedir E. Evaluation of the potential aphrodisiac activity of sesquiterpenoids from roots of Ferula hubermorathii Peşmen in male rats. J Ethnopharmacol [Internet]. 2020;257(112868):112868. Available from: http://dx.doi.org/10.1016/j.jep.2020.112868 DOI: https://doi.org/10.1016/j.jep.2020.112868

Choudhury MRA, Basak M. Ethno medicinal plants used for aphrodisiac activity in North- East, India. J Pharm Res Int [Internet]. 2021;314–22. Available from: http://dx.doi.org/10.9734/jpri/2021/v33i38b32 129 DOI: https://doi.org/10.9734/jpri/2021/v33i38B32129

Gupta M, Mondal AK. Clinical evaluation of aphrodisiac activity of a novel ayurvedic formulation for treatment of male sexual disorders. Int J Res Med Sci [Internet]. 2020;8(7):2515. Available from: http://dx.doi.org/10.18203/2320- 6012.ijrms20202888 DOI: https://doi.org/10.18203/2320-6012.ijrms20202888

Vasantrao US, Biyani KR. Evaluation of Preclinical Aphrodisiac Activity of Flueggea leucopyrus Willd. Leaves. Curr Bioact Compd [Internet]. 2020;16(3):335–41. Available from: http://dx.doi.org/10.2174/1573407214666181 105115510 DOI: https://doi.org/10.2174/1573407214666181105115510

Kadzo L. Aphrodisiac Activity of Pomegranate (Punica granatum L.) fruit extract on the sexual function in rats. Discov Phytomedicine [Internet]. 2020;7(2). Available from: http://dx.doi.org/10.15562/phytomedicine.2020.121 DOI: https://doi.org/10.15562/phytomedicine.2020.121

Du Q, Huang Y-H, Bajpai A, Frosig- Jorgensen M, Zhao G, Craik DJ. Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus. J Nat Prod [Internet]. 2020;83(12):3736–43. Available from: http://dx.doi.org/10.1021/acs.jnatprod.0c0104 5 DOI: https://doi.org/10.1021/acs.jnatprod.0c01045

Aphrodisiac activity of vanari gutika formulated using milk obtained from jersey cow (Bos taurus), indigenous cow (Bos indicus) and buffalo (Bubalus bubalis). Ind J Tradit Knowl [Internet]. 2020;19(3). Available from: http://dx.doi.org/10.56042/ijtk.v19i3.41480 DOI: https://doi.org/10.56042/ijtk.v19i3.41480

Oboh G, Adebayo AA, Ademosun AO, Abegunde OA. Aphrodisiac effect of Hunteria umbellata seed extract: Modulation of nitric oxide level and arginase activity in vivo. Pathophysiology [Internet]. 2019;26(1):39–47. Available from: http://dx.doi.org/10.1016/j.pathophys.2018.11.003 DOI: https://doi.org/10.1016/j.pathophys.2018.11.003

Borkar SS, Mahapatra DK, Usare S. Reviewing the aphrodisiac activity of lepedium meyenii plant in modern contexts. In: Natural Products Pharmacology and Phytochemicals for Health Care. Includes bibliographical references and index.: Apple Academic Press; 2020. p. 41–54. DOI: https://doi.org/10.1201/9781003057932-3

Karunanithi M, David Raj C, Jegadeesan M, Kavimani S. Phytochemical analysis and comparative aphrodisiac activity of four species of Mucuna. In: Phytopharmaceuticals and Drug Delivery Approaches. Avid Science; 2019. p. 02–29. DOI: https://doi.org/10.29290/PDDA.1.4.2019.2-29